Welcome!

STREAM is a collaboration of researchers who share a common set of principles about the goals and methods for studying clinical translation. We apply empirical and philosophical tools for addressing scientific, ethical, and policy challenges in the development and translation of health technologies. Our members work in ethics, epidemiology, biology, psychology, and various medical specialties. The network is centered at McGill University, and has affiliates throughout North America.

Job Postings

We are currently inviting applications for a new postdoctoral fellow with a background in the decision sciences, psychology or behavioral methods, clinical trials, or ethics. The project will examine how well researchers and other experts can be trained to forecast risks, benefits, and feasibility of clinical trials. Anticipated start date is Summer 2016. Those interested can read the full position posting here!

We are also inviting applications for a full-time casual research assistant for a project on Personalized Medicine and the ethical dimensions of risk. The preferred candidate will have an undergraduate degree in a life science (e.g. Physiology, Neuroscience) and must be prepared to commit for one year with STREAM, preferably two. Read the full position posting here!

News

Jonathan Kimmelman appointed to the Editorial Board of PLoS Biology, which is initiating a new meta-science section.

Work of STREAM profiled in Nature Reviews Clinical Oncology

Recent Awards

Congratulations to Benjamin Carlisle, the winner of the 2015 Rabinowitch Fellowship!

Our Latest Publications

Grankvist H and Kimmelman J. How do researchers decide early clinical trials? Medicine, Health Care and Philosophy 2016.

Kimmelman J, Henderson VC. Assessing risk/benefit for trials using preclinical evidence: a proposal. Journal of Medical Ethics 2015; DOI: doi:10.1136/medethics-2015-102882

Carlisle B, Demko N, Freeman G, Hakala A, MacKinnon N, Ramsay T, Hey SP, London AJ, Kimmelman J. Benefit, Risk, and Outcomes in Drug Development: A Systematic Review of Sunitinib JNCI 2015; DOI: 10.1093/jnci/djv292

London AJ, Kimmelman J. Point of view: Why clinical translation cannot succeed without failure. eLife4:e12844. 2015.

Henderson VC, Demko N, Hakala A, MacKinnon N, Federico CA, Fergusson D, Kimmelman J. A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib. eLife4:e08351. 2015.


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