STREAM is a collaboration of researchers who share a common set of principles about the goals and methods for studying clinical translation. We apply empirical and philosophical tools for addressing scientific, ethical, and policy challenges in the development and translation of health technologies. Our members work in ethics, epidemiology, biology, psychology, and various medical specialties. The network is centered at McGill University, and has affiliates throughout North America and abroad.
Kimmelman J, Tannock, I. The paradox of precision medicine. Nature Reviews Clinical Oncology, April 19, 2018.
London A, Kimmelman J. Clinical Trials in Medical Center Advertising, JAMA Oncology, April 5, 2018.
Companion opinion piece: Cancer centers sell out science when they advertise clinical trials as treatment, STAT, April 25, 2018.
Carlisle B, Federico C, Kimmelman J. Trials that say “maybe”: the disconnect between exploratory and confirmatory testing after drug approval, The BMJ, March 20, 2018.
Marcin Waligora, Malgorzata M. Bala , Magdalena Koperny, Mateusz T. Wasylewski, Karolina Strzebonska, Rafał R. Jaeschke, Agnieszka Wozniak, Jan Piasecki, Agnieszka Sliwka, Jerzy W. Mitus, Maciej Polak, Dominika Nowis, Dean Fergusson, Jonathan Kimmelman. Risk and surrogate benefit for pediatric Phase I trials in oncology: A systematic review with meta-analysis. PLoS Medicine. February 2018.
Jonathan Kimmelman quoted in Bloomberg, on the ethics of self-experimentation.
Jonathan Kimmelman quoted in WJCT, on the unrealistic expectations created by cancer center clinical trial advertisements.
Jonathan Kimmelman quoted in the National Post, on the ethics of synthetic human embryos.
Science coverage of research co-authored by doctoral candidate Carole Federico and Jonathan Kimmelman, on reliability of animal efficacy data.
Jonathan Kimmelman quoted in National Post, on why patients deserve post-trial access to drugs they appear to have benefited from.
Jonathan Kimmelman quoted in Medical Republic article on animal studies and translational research.
Can cancer researchers accurately judge whether preclinical reports will reproduce? described as one of the biggest media hits at PLoS Bio for 2017.
Jonathan Kimmelman in Bloomberg News article about CRISPR.
STAT News coverage of recent research from Jonathan Kimmelman and colleagues showing that cancer experts are not very accurate at forecasting results of clinical trials.
Jonathan Kimmelman quoted in CBC News: "Should we let the crowd fund Canadian science if no one else will?"