Much has already been said about Filing Cabinet syndrome in medical research: the tendency of researchers to publish exciting results from clinical trials, and to stash null or negative findings safely away from public view in a filing cabinet. Nonpublication distorts the medical literature, because it prevents medical practitioners from accessing negative information about drugs. Recall that, back in 2004, attorney-general Eliot Spitzer sued Glaxo Smithkline for suppressing trial results that showed elevated risk of suicide for adolescents taking the antidepressant drug Paxil; this and several similar episodes led FDA, major medical journals, World Health Organization, World Medical Association, and others to require researchers to register clinical trials before they enroll any patients.
BibTeX
@Manual{stream2010-66, title = {Filing Cabinet Syndrome: The Effect of Nonpublication of Preclinical Research}, journal = {STREAM research}, author = {Jonathan Kimmelman}, address = {Montreal, Canada}, date = 2010, month = may, day = 11, url = {http://www.translationalethics.com/2010/05/11/filing-cabinet-syndrome-the-effect-of-nonpublication-of-preclinical-research/} }
MLA
Jonathan Kimmelman. "Filing Cabinet Syndrome: The Effect of Nonpublication of Preclinical Research" Web blog post. STREAM research. 11 May 2010. Web. 14 Oct 2024. <http://www.translationalethics.com/2010/05/11/filing-cabinet-syndrome-the-effect-of-nonpublication-of-preclinical-research/>
APA
Jonathan Kimmelman. (2010, May 11). Filing Cabinet Syndrome: The Effect of Nonpublication of Preclinical Research [Web log post]. Retrieved from http://www.translationalethics.com/2010/05/11/filing-cabinet-syndrome-the-effect-of-nonpublication-of-preclinical-research/
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