Semantic natural language processing and philosophy of science

On 2015 February 18, James Overton visited the STREAM research group in Montreal, where he presented his research into what scientists are doing when give an explanation for something. Many accounts of scientific explanation have been offered by philosophers of science over the years, but Overton’s offering differs in that he set out to establish… Continue reading Semantic natural language processing and philosophy of science

Unsuccessful trial accrual and human subjects protections: An empirical analysis of recently closed trials

The moral acceptability of a clinical trial is rooted in the risk and benefit for patients, as well as the ability of the trial to produce generalisable and useful scientific knowledge. The ability of a clinical trial to justify its claims to producing new knowledge depends in part on its ability to recruit patients to… Continue reading Unsuccessful trial accrual and human subjects protections: An empirical analysis of recently closed trials

When is it legitimate to stop a clinical trial early?

Inspired by a paper that I’m working on with a few of my colleagues from the STREAM research group on the subject of the accrual of subjects in human research, I’ve been reading through a number of articles related to the question, When is it legitimate to stop a clinical trial that is already in progress?… Continue reading When is it legitimate to stop a clinical trial early?