News Coverage



Interactive AERO graph showing patient risk and benefit over the cancer research life-cycle of the tyrosine kinase inhibitor, sunitinib. Data taken from a 2015 STREAM publication in JNCI.


Jonathan Kimmelman’s talk “Ethics, Randomized Trials, and Clinical Equipoise” for UAB’s Nutrition Obesity Health Center’s investigator training program.

Jonathan Kimmelman’s talk “Reproducibility in Preclinical Research: Activities in Opportunities” from Reproducibility in a Changing Research Landscape: a workshop of the Roundtable on Science and Welfare in Laboratory Animal Use at the National Academy of Sciences (June 4-5, 2014).


Jonathan Kimmelman on Research Ethics and Dilemmas in Clinical Trials, The Scope of Things Podcast, Episode #28, July 9, 2024.

COVID-19 : Quel bilan tirer des prépublications scientifiques?, CBC’s Radio Canada, January 18, 2020.

The Pandemic Is Pushing Scientists To Rethink How They Read Research Papers, NPR’s Morning Edition, July 07, 2020.

The race for a COVID-19 vaccineCBC The National, April 15, 2020.

Statisticians asked to remove, ignore data to aid researchers: study, live interview on CTV’s Your Morning on Monday, October 22, 2018.

Les cobayes de Sainte-Justine: Des chercheurs ont bâclé une étude clinique sur des enfants, Radio Canada, October 4, 2018.

In Psychology And Other Social Sciences, Many Studies Fail The Reproducibility Test, NPR: All Things Considered, August 27, 2018.

Scientists Are Not So Hot At Predicting Which Cancer Studies Will Succeed, NPR: All Things Considered, July 4, 2017 (link to article here).

Interview with Prof. Jonathan Kimmelman, Second Opinion (CBC), February 2, 2017. Second Opinion speaks with Prof. Jonathan Kimmelman, whose commentary about raising the bar for approving first-in-human clinical trials appeared in the journal Nature this week.

From Concept To Market: Ethical Questions In Drug Research, Vermont Edition (NPR), October 12, 2015.

Patient-funded clinical trials may do more harm than good, The Current (CBC), August 14, 2015.


The Effect of Cancer Trials on Their ParticipantsScience, June 18, 2024.

Lo que se desconoce de los fármacos experimentales contra el cáncer, elPeriódico, June 15, 2024.

Cancer: quels bienfaits pour les participants aux essais cliniques?, Le Nord-Côtier, May 26, 2024.

Joining a cancer trial doesn’t improve survival odds, Science, May 22, 2024.

Cancer Clinical Trial Participation May Not Actually Improve Survival, Study Says, MedPage Today, May 22, 2024.

Foundation stirs controversy by charging cancer patients $83,000 for unproven but promising experimental drug, The Boston Globe, March 4, 2023.

A massive 8-year effort finds that much cancer research can’t be replicated, Science News, December 7, 2021.

How Canadian researchers are using stem cell advances to transform medicine, The Globe and Mail, December 2, 2021.

‘It’s misinformation at worst.’ Weak health studies can do more harm than good, scientists say, Science, December 2, 2021.

Philanthropist-funded study at a prestigious hospital raises thorny questions about clinical research, STAT, October 20, 2021.

When To Stop Hoping For a COVID-19 Miracle Cure, FiveThirtyEight, August 4, 2021.

Bolstered by Texas A&M and slim evidence, Ben Carson prompted tests of a COVID-19 remedy on seniors, The Dallas Morning News, July 15, 2021.

Can Botox ease depression by eliminating frowns? Researchers have doubts, Science, June 24, 2021.

Clinical Trials with One Subject Raise Ethical Questions, IRB Advisor, June 1, 2021.

Ethical Considerations Before Launching a Clinical Cancer Trial, The ASCO Post, April 25, 2021.

Why the credibility of AstraZeneca’s vaccine data matters. Axios, March 24, 2021.

What Happens When You Can’t Reproduce? The Harvard Crimson, March 23, 2021.

Halving and delaying doses of vaccines a big gamble on limited science. The National Post, January 08, 2021.

De nouveaux écueils sur la route des vaccins, La Presse, December 20, 2020. 

Why Canada’s vaccine rollout won’t be easy Maclean’s, December 8, 2020.

6 Ways the Coronavirus Pandemic Changed Science Discover Magazine, December 3, 2020.

‘People of poorer nations have moral claim to be at the front of the queue when vaccines arrive’ Open Magazine, November 21, 2020.

‘I just want to see the evidence’: Scientists want more data to confirm Pfizer vaccine is 90 per cent effective The National Post, November 10, 2020.

When it comes to COVID-19 vaccines, how good will be good enough? The National Post, October 28, 2020.

Florida Man’s COVID-19 antibody cocktail is promising but untested. The Sydney Morning Herald, October 7, 2020.

S’infecter délibérément pour la science. La Presse, October 1, 2020.

How the Coronavirus Pandemic May Affect Cancer Clinical Trials. Cancer Therapy Advisor, September 23th, 2020.

Pfizer’s COVID vaccine trial plan may beat rivals to early look. Bloomberg News, September 22, 2020.

Rush to approve Covid vaccine prompted by politics may end in disasterChemistry World, September 16th, 2020.

Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency. Nature, September 14th, 2020.

Challenge trials face too many ethical and logistical hurdles to go forward, experts say. The Hill Times, September 14th, 2020.

A leading coronavirus vaccine trial is on hold: scientists react. Nature, September 09, 2020.

Is the rush to roll out a coronavirus vaccine undermining safety? NewScientist, August 26, 2020.

Ergebnisse sollten nicht gleich für alle Welt freigegeben werden. Zeit Online, June 13, 2020.

Hastigheten er ekstrem. Mengden er enorm. Mye står på spill. Morgenbladet, May 29, 2020.

Stanford coronavirus research: Did politically-motivated scientists hype their speedy study?, The Mercury News, May 24, 2020.

Ethics questions swirl around historic Parkinson’s experiment, STAT News, May 14, 2020.

A New Look at the Dose-Response Relationship in Phase 1 Oncology Trials, Cancer Therapy Advisor, May 13, 2020.

Inside the extraordinary race to invent a coronavirus vaccine, The Washington Post, May 3, 2020.

Gare à l’infection volontaireLa Presse, April 30, 2020.

En kris är ingen ursäkt för sänkta krav på forskning [A crisis is no excuse for lowered research requirements], Dagens Nyheter, April 26, 2020.

Shortcuts in COVID-19 Drug Research Could Do Long-Term Harm, Bioethicists WorryScientific American, April 24, 2020.

Die Gefahren einer allzu hektischen Covid-19-Forschung [The dangers of overly hasty Covid-19 research], Der Tagesspiegel, April 24, 2020.

Stop Getting So Excited About ‘Preliminary’ FindingsWired, April 24, 2020.

La crise n’est pas une raison pour assouplir les normes scientifiques et éthiques, selon des expertsLe Devoir, April 23, 2020.

Attention aux dérives de la recherche clinique, disent des chercheurs, Radio Canada, April 23, 2020.

Alertan de la baja calidad de numerosos estudios sobre el coronavirus [Warning on the low quality of numerous studies on coronavirus], El Mundo, April 23, 2020.

‘We have a whole globe to protect’: Pandemic vaccine research speeds upCBC News, April 16, 2020.

New clinical trials bring potential COVID-19 treatments to North TexasDallas News, March 28, 2020.

WHO Malaria Vaccine ‘Rollout’ In Africa Raises Ethical QuestionsClinical Research News, March 26, 2020.

What are the rules of social distancing?Vox, March 15, 2020.

Researchers rush to test coronavirus vaccine in people without knowing how well it works in animalsSTAT News, March 11, 2020.

WHO’s malaria vaccine study represents a “serious breach of international ethical standards”, BMJ, February 26, 2020.

Miracle Cancer Drugs Are Making Big Pharma Billions. Others Are Getting Left BehindBloomberg, December 12, 2019.

In Hunting for Cures, Ethics Can Strengthen Clinical TrialsCarnegie Mellon News, November 6, 2019.

The potent effects of Japan’s stem-cell policies, Nature News, September 25, 2019.

Should Alzheimer’s Prevention Trials Include Disease-Modifying Therapies? Experts Weigh the Risks and BenefitsNeurology Today, September 19, 2019.

Animal registries aim to reduce biasNature News, September 9, 2019.

Stem cell hypeChemistry World, September 9, 2019.

Crispr Babies Vs. ‘Bubble Boy’: Only One Was About the Patient, Bloomberg, April 30, 2019.

The study of a cancer test seemed like a triumph. But some data were missing, STAT News, April 12, 2019.

China to tighten rules on gene editing in humans, Nature, March 6, 2019.

The CRISPR-baby scandal: what’s next for human gene-editing, Nature, February 26, 2019.

Unconfirmed exploratory trials after approvals may cause too much off-label prescribing, STAT News, December 12, 2018.

When Clinical Trials Are Marketing Ploys, Not Science, Forbes, November 28, 2018.

When scientists want their data fudged and why you should care, Second Opinion (CBC), October 13, 2018.

A McKinney family and UT Southwestern scientists race to save boy with ultra-rare disease, Dallas News, August 15, 2018.

Warning: Don’t Try This Biohacking at Home, Bloomberg, June 5, 2018.

Clinical Trials: Doctors Want Participation And Bioethicists Warn Against Unrealistic Expectations, WJCT, May 29, 2018.

‘Synthetic’ human embryos are on the horizon, but ethics surrounding them are complicated, The National Post, April 29, 2018.

Cancer centers sell out science when they advertise clinical trials as treatment, STAT, April 25, 2018.

Are Clinical Trials Being Oversold to Cancer Patients? Medscape, April 16, 2018.

Study questions animal efficacy data behind trials, Science, April 13, 2018.

Clinical trials may be based on flimsy animal data, Science, April 5, 2018.

Mom fears losing access to experimental drug that helped daughter after study ends, National Post, March 26, 2018.

New study raises questions about early-stage cancer therapies for children, STAT News, February 20, 2018.

Mice are mini-humans and the moon is made of cheese, The Medical Republic, February 19, 2018.

Biggest Hits – PLOS Biology in the Media in 2017, PLoS, January 16, 2018; citing Can cancer researchers accurately judge whether preclinical reports will reproduce?

Scientists Don’t Fear a New Crispr Snag, Bloomberg News, January 23, 2018.

How well can you predict the outcome of clinical trials? Not as well as you may think, STAT News, January 22, 2018.

Should we let the crowd fund Canadian science if no one else will?, CBC, January 20, 2018.

Investigation Raises Concerns About Animal Study Misreporting, MedPage Today, January 10, 2018.

Universities accused of unethical ‘pick and mix’ reporting of drug trial results, The Telegraph, January 10, 2018.

Oxford vaccine study highlights pick and mix approach to preclinical research, The BMJ, January 10, 2018.

Tiny human brain organoids implanted into rodents, triggering ethical concerns, STAT News, November 6, 2017.

In need of scrutiny: Misleading stem cell claims by academic medical centers, Health News Review, November 2, 2017.

Prospect of Synthetic Embryos Sparks New Bioethics Debate, MIT Technology Review, September 19, 2017.

Discrepancy between trial goals, results may mask treatment risks, Reuters, September 13, 2017.

Study: Trial Results for New Neurological Drugs Often Go Unpublished, Medical Ethics Advisor, August 1, 2017.

Chinese rocket failure, Fukushima trial and discarded fish [The week in science: 30 June–6 July 2017], Nature, July 5, 2017.

Scientists Are Not So Hot At Predicting Which Cancer Studies Will Succeed, NPR: All Things Considered, July 4, 2017 (link to audio here).

Preclinical Cancer Studies Not as Reproducible as Thought, The Scientist, June 30, 2017.

Cancer scientists may overestimate reliability of mouse studies, Reuters, June 29, 2017.

Authors retract much-debated blockchain paper from F1000, Retraction Watch, May 24, 2017.

Stem Cell Trial Data Mostly Go Unpublished, The Scientist, May 5, 2017.

The Readout, STAT, January 31, 2017.

Ethiker fordern strengere Kontrollen bei Phase-I-Studien, DAZ, January 31, 2017.

Des essais cliniques inutiles, La Presse, January 30, 2017.

After trial death and before Florida Man change, a call for drug approval reform, CNN, January 30, 2017.

Why the bar needs to be raised for human clinical trials, Science Daily, January 30, 2017.

Questionable “Young Blood” Transfusions Offered in U.S. as Anti-Aging Remedy, MIT Technology Review, January 13, 2017.

A Death and Other Adverse Events in French Drug Trial Raise Questions About Testing Safety and Ethics, Neurology Today, December 8, 2016.

Des effets secondaires des médicaments restent absents des publications scientifiques, Le Devoir, September 24, 2016.

Brunswick woman taking gamble that stem cells will restore vision, Portland Press Herald, August 1, 2016.

Is Most Clinical Research Useless?, Canadian Medical Association Journal, July 12, 2016.

Journalists: 9 tips to combat stem cell hype in your news stories, Health News Review, June 27, 2016.

Guidelines on stem cell research put patients first, warn against hype, Maclean’s, May 12, 2016.

After Infecting Pregnant Monkey With Zika, Scientists Wait for Backlash, KQED Science, March 22, 2016.

Got a Single Observation? New Journal Will Publish It, Science Insider, December 2, 2015.

Poor quality animal studies cause clinical trials to follow false leads, BMJ Research News, October 15, 2015.

Development of treatments affected by ‘poorly designed’ animal experiments, The Bolton News, October 15, 2015.

How 74 years of flawed experiments ‘hampered’ cancer fight, The Scotsman, October 14, 2015.

Expert reaction to study examining the reproducibility of cancer research, Science Media Centre, October 13, 2015.

Much of preclinical research into one cancer drug is flawed, says report, Retraction Watch, October 13, 2015.

Poorly-designed animal experiments in the spotlight, Nature, October 13, 2015.

Drugs research hampered by substandard animal testing procedures, The Guardian, October 13, 2015.

Ces recherches qui se perdent, Le Devoir, August 31, 2015.

Trend sees patients paying for their own clinical trials, but critics raise ethical concerns, National Post, August 12, 2015.

US societies push back against NIH reproducibility guidelines, Nature, April 17, 2015.

Data on failed drug experiments rarely made public, McGill study finds, The Globe and Mail, March 13, 2015.

Protection Without a Vaccine, NY Times, March 9, 2015.

Canadian Ebola vaccine weeks away from human testing, The Globe and Mail, August 28, 2014.

The Elusive Heart Fix, Science Magazine, July 18, 2014.

Stem Cell Treatments Overtake Science, NY Times, September 9, 2013.

Can We Eliminate Animals from Medical Research? PBS, Aug 7, 2013.

Improving Preclinical Research. Genetic Engineering News, July 31, 2013.

Flaws in medical experiments on animals ‘a waste’. CBC News, July 23, 2013.

Study Finds Rampant Bias in Animal-Based Drug Research. The Chronicle of Higher Education, July 16, 2013.

Ethical Considerations in Phase II Trials.  Genetic Engineering News, May 8, 2013.

In Search of Genomic Incentives (OpEd).  Globe and Mail, December 19, 2012.

Cancer Trials Lack Clear Information on Biopsies.  Reuters, November 8, 2012.

DNA Experiment Yields Great Promise and High Ethical Risks.  Washington Post, October 25, 2012.

Q&A: Improving Preclinical Trials.  The Scientist, March 8, 2011.

Experts Call for Stricter Regulations in Clinical Trials of New Drugs.  Pittsburgh Post Gazette, March 14, 2011.


    title = {News Coverage},
    journal = {STREAM research},
    author = {Katerina Carayannis},
    address = {Montreal, Canada},
    date = 2013,
    month = jun,
    day = 22,
    url = {}


Katerina Carayannis. "News Coverage" Web blog post. STREAM research. 22 Jun 2013. Web. 19 Jul 2024. <>


Katerina Carayannis. (2013, Jun 22). News Coverage [Web log post]. Retrieved from

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