Interactive AERO graph showing patient risk and benefit over the cancer research life-cycle of the tyrosine kinase inhibitor, sunitinib. Data taken from a 2015 STREAM publication in JNCI.


Jonathan Kimmelman’s talk “Reproducibility in Preclinical Research: Activities in Opportunities” from Reproducibility in a Changing Research Landscape: a workshop of the Roundtable on Science and Welfare in Laboratory Animal Use at the National Academy of Sciences (June 4-5, 2014).

Radio and Television

Statisticians asked to remove, ignore data to aid researchers: study, live interview on CTV’s Your Morning on Monday, October 22, 2018.

Les cobayes de Sainte-Justine: Des chercheurs ont bâclé une étude clinique sur des enfants, Radio Canada, October 4, 2018.

In Psychology And Other Social Sciences, Many Studies Fail The Reproducibility Test, NPR: All Things Considered, August 27, 2018.

Scientists Are Not So Hot At Predicting Which Cancer Studies Will Succeed, NPR: All Things Considered, July 4, 2017 (link to article here).

Interview with Prof. Jonathan Kimmelman, Second Opinion (CBC), February 2, 2017. Second Opinion speaks with Prof. Jonathan Kimmelman, whose commentary about raising the bar for approving first-in-human clinical trials appeared in the journal Nature this week.

From Concept To Market: Ethical Questions In Drug Research, Vermont Edition (NPR), October 12, 2015.

Patient-funded clinical trials may do more harm than good, The Current (CBC), August 14, 2015.


Animal registries aim to reduce biasNature News, September 9, 2019.

Stem cell hypeChemistry World, September 9, 2019.

Crispr Babies Vs. ‘Bubble Boy’: Only One Was About the Patient, Bloomberg, April 30, 2019.

The study of a cancer test seemed like a triumph. But some data were missing, STAT News, April 12, 2019.

China to tighten rules on gene editing in humans, Nature, March 6, 2019.

The CRISPR-baby scandal: what’s next for human gene-editing, Nature, February 26, 2019.

Unconfirmed exploratory trials after approvals may cause too much off-label prescribing, STAT News, December 12, 2018.

When Clinical Trials Are Marketing Ploys, Not Science, Forbes, November 28, 2018.

When scientists want their data fudged and why you should care, Second Opinion (CBC), October 13, 2018.

A McKinney family and UT Southwestern scientists race to save boy with ultra-rare disease, Dallas News, August 15, 2018.

Warning: Don’t Try This Biohacking at Home, Bloomberg, June 5, 2018.

Clinical Trials: Doctors Want Participation And Bioethicists Warn Against Unrealistic Expectations, WJCT, May 29, 2018.

‘Synthetic’ human embryos are on the horizon, but ethics surrounding them are complicated, The National Post, April 29, 2018.

Cancer centers sell out science when they advertise clinical trials as treatment, STAT, April 25, 2018.

Are Clinical Trials Being Oversold to Cancer Patients? Medscape, April 16, 2018.

Study questions animal efficacy data behind trials, Science, April 13, 2018.

Clinical trials may be based on flimsy animal data, Science, April 5, 2018.

Mom fears losing access to experimental drug that helped daughter after study ends, National Post, March 26, 2018.

New study raises questions about early-stage cancer therapies for children, STAT News, February 20, 2018.

Mice are mini-humans and the moon is made of cheese, The Medical Republic, February 19, 2018.

Biggest Hits – PLOS Biology in the Media in 2017, PLoS, January 16, 2018; citing Can cancer researchers accurately judge whether preclinical reports will reproduce?

Scientists Don’t Fear a New Crispr Snag, Bloomberg News, January 23, 2018.

How well can you predict the outcome of clinical trials? Not as well as you may think, STAT News, January 22, 2018.

Should we let the crowd fund Canadian science if no one else will?, CBC, January 20, 2018.

Investigation Raises Concerns About Animal Study Misreporting, MedPage Today, January 10, 2018.

Universities accused of unethical ‘pick and mix’ reporting of drug trial results, The Telegraph, January 10, 2018.

Oxford vaccine study highlights pick and mix approach to preclinical research, The BMJ, January 10, 2018.

Tiny human brain organoids implanted into rodents, triggering ethical concerns, STAT News, November 6, 2017.

In need of scrutiny: Misleading stem cell claims by academic medical centers, Health News Review, November 2, 2017.

Prospect of Synthetic Embryos Sparks New Bioethics Debate, MIT Technology Review, September 19, 2017.

Discrepancy between trial goals, results may mask treatment risks, Reuters, September 13, 2017.

Chinese rocket failure, Fukushima trial and discarded fish [The week in science: 30 June–6 July 2017], Nature, July 5, 2017.

Scientists Are Not So Hot At Predicting Which Cancer Studies Will Succeed, NPR: All Things Considered, July 4, 2017 (link to audio here).

Preclinical Cancer Studies Not as Reproducible as Thought, The Scientist, June 30, 2017.

Cancer scientists may overestimate reliability of mouse studies, Reuters, June 29, 2017.

Authors retract much-debated blockchain paper from F1000, Retraction Watch, May 24, 2017.

Stem Cell Trial Data Mostly Go Unpublished, The Scientist, May 5, 2017.

The Readout, STAT, January 31, 2017.

Ethiker fordern strengere Kontrollen bei Phase-I-Studien, DAZ, January 31, 2017.

Des essais cliniques inutiles, La Presse, January 30, 2017.

After trial death and before Trump change, a call for drug approval reform, CNN, January 30, 2017.

Why the bar needs to be raised for human clinical trials, Science Daily, January 30, 2017.

Questionable “Young Blood” Transfusions Offered in U.S. as Anti-Aging Remedy, MIT Technology Review, January 13, 2017.

A Death and Other Adverse Events in French Drug Trial Raise Questions About Testing Safety and Ethics, Neurology Today, December 8, 2016.

Des effets secondaires des médicaments restent absents des publications scientifiques, Le Devoir, September 24, 2016.

Brunswick woman taking gamble that stem cells will restore vision, Portland Press Herald, August 1, 2016.

Is Most Clinical Research Useless?, Canadian Medical Association Journal, July 12, 2016.

Journalists: 9 tips to combat stem cell hype in your news stories, Health News Review, June 27, 2016.

Guidelines on stem cell research put patients first, warn against hype, Maclean’s, May 12, 2016.

After Infecting Pregnant Monkey With Zika, Scientists Wait for Backlash, KQED Science, March 22, 2016.

Got a Single Observation? New Journal Will Publish It, Science Insider, December 2, 2015.

Poor quality animal studies cause clinical trials to follow false leads, BMJ Research News, October 15, 2015.

Development of treatments affected by ‘poorly designed’ animal experiments, The Bolton News, October 15, 2015.

How 74 years of flawed experiments ‘hampered’ cancer fight, The Scotsman, October 14, 2015.

Expert reaction to study examining the reproducibility of cancer research, Science Media Centre, October 13, 2015.

Much of preclinical research into one cancer drug is flawed, says report, Retraction Watch, October 13, 2015.

Poorly-designed animal experiments in the spotlight, Nature, October 13, 2015.

Drugs research hampered by substandard animal testing procedures, The Guardian, October 13, 2015.

Ces recherches qui se perdent, Le Devoir, August 31, 2015.

Trend sees patients paying for their own clinical trials, but critics raise ethical concerns, National Post, August 12, 2015.

US societies push back against NIH reproducibility guidelines, Nature, April 17, 2015.

Data on failed drug experiments rarely made public, McGill study finds, The Globe and Mail, March 13, 2015.

Protection Without a Vaccine, NY Times, March 9, 2015.

Canadian Ebola vaccine weeks away from human testing, The Globe and Mail, August 28, 2014.

The Elusive Heart Fix, Science Magazine, July 18, 2014.

Stem Cell Treatments Overtake Science, NY Times, September 9, 2013.

Can We Eliminate Animals from Medical Research? PBS, Aug 7, 2013.

Improving Preclinical Research. Genetic Engineering News, July 31, 2013.

Flaws in medical experiments on animals ‘a waste’. CBC News, July 23, 2013.

Study Finds Rampant Bias in Animal-Based Drug Research. The Chronicle of Higher Education, July 16, 2013.

Ethical Considerations in Phase II Trials.  Genetic Engineering News, May 8, 2013.

In Search of Genomic Incentives (OpEd).  Globe and Mail, December 19, 2012.

Cancer Trials Lack Clear Information on Biopsies.  Reuters, November 8, 2012.

DNA Experiment Yields Great Promise and High Ethical Risks.  Washington Post, October 25, 2012.

Q&A: Improving Preclinical Trials.  The Scientist, March 8, 2011.

Experts Call for Stricter Regulations in Clinical Trials of New Drugs.  Pittsburgh Post Gazette, March 14, 2011.


    title = {Media},
    journal = {STREAM research},
    author = {STREAM admin},
    address = {Montreal, Canada},
    date = 2013,
    month = jun,
    day = 22,
    url = {}


STREAM admin. "Media" Web blog post. STREAM research. 22 Jun 2013. Web. 17 Oct 2019. <>


STREAM admin. (2013, Jun 22). Media [Web log post]. Retrieved from

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