VI. Gene & Cell-Based Interventions


Gene & Cell-Based Interventions

MacPherson A and Kimmelman J. Ethical development of stem-cell-based interventions. Nature Medicine, 2019.

Hey SP and Kimmelman J. The Risk-Escalation Model: A Principled Design Strategy for Early-Phase Trials. Kennedy Institute of Ethics Journal, 2014.

Anderson JA and Kimmelman J.  Ethics and Uncertainty: Considerations for the Design and Review of Translational Trials Involving Stem Cells.  In:  Translational Stem Cell Research: Issues Beyond the Debate on the Moral Status of the Embryo. Hug K, Hermerén G, eds.  New York: Springer, 2010.

Kimmelman J. Gene Transfer and the Ethics of First-in-Human Experiments: Lost in Translation. New York: Cambridge University Press, 2009.

Kimmelman J. Ethics of Cancer Gene Transfer Clinical Research.  In W. Walther, U. Stein, eds.  Gene Therapy of Cancer.  Humana Press: Totowa, NJ, 2008.

Kimmelman J. The Ethics of Human Gene Transfer. Nature Reviews—Genetics, 2008.

Kimmelman J. Staunch protections: the ethics of haemophilia gene transfer research. Haemophilia, 2007.

Kimmelman J. Recent developments in gene transfer: risk and ethics. BMJ, 2005.