Heaven help those perseverant souls who pursue translational research on neurodegnerative disorders. New interventions in this area have just about the highest failure rate of any area of medical research. And last week, yet another promising strategy was shown ineffective in a phase II study. The trial in question was testing Ceregene’s gene transfer strategy… Continue reading Sourgene
Tag: neurodegenerative diseases
The Problem with Models
Chicago in plastic and balsa. If only animal models were as convincing as the one pictured above from the Museum of Science and Industry. The August 7 issue of Nature ran a fascinating feature on how many scientists are reassessing the value of animal models used in neurodegenerative preclinical research (“Standard Model,” by Jim Schnabel).… Continue reading The Problem with Models